What Are Systemic Enzymes?

Systemic enzymes are proteolytic (protein-digesting) enzymes that, when taken on an empty stomach, enter the bloodstream rather than being used solely for digestion. Once in circulation, these enzymes help the body: Break down excess inflammatory proteins Support normal tissue repair processes Assist in clearing cellular debris from injured areas Unlike ingredients that simply “feed” the joints, systemic enzymes work by helping regulate the biochemical environment that drives inflammation throughout the body. This is particularly important in dogs dealing with:       

• Joint degeneration  

Ligament injuries (such as CCL strains)

Muscle inflammation

Post-exercise soreness

Post-surgical recovery

How Arto Velox™ Enzymes Work in the Body

The Arto Velox proprietary blend in FORTE FLEX K9 is designed to support multiple stages of the inflammatory and recovery process, not just one pathway.

1.Serrapeptase: Supporting Inflammatory Protein Breakdown

Serrapeptase is a proteolytic enzyme originally derived from beneficial bacteria and widely studied for its ability to break down non-living protein matter, including excess fibrin and inflammatory byproducts. Research suggests serrapeptase may help:

Reduce swelling by breaking down inflammatory debris 

Support tissue oxygenation 

Improve circulation in affected areas

By helping the body clear protein waste associated with inflammation, serrapeptase supports a healthier recovery environment — which can translate to improved comfort and mobility over time.

Reference: Serrapeptase and inflammation mechanisms — International Journal of Surgery https://www.sciencedirect.com/science/article/pii/S1743919112000643

2. Bromelain: Supporting Soft Tissue and Joint Comfort

Bromelain, derived from pineapple stems, has been widely studied for its role in: 

Supporting joint comfort

Reducing post-exercise muscle soreness 

Assisting in swelling management

Bromelain may influence inflammatory mediators and help regulate the body’s response to tissue stress. In veterinary and human applications, it has been explored as a supportive option for musculoskeletal recovery and joint stiffness. When combined with other systemic enzymes, bromelain can enhance the overall effectiveness of inflammation support strategies.

Reference: Bromelain’s effects on inflammation — Biotechnology Research International https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529416/

3. Papain: Assisting Protein Breakdown and Tissue Recovery

Papain, derived from papaya, is another proteolytic enzyme that helps: 

Break down damaged proteins

Support soft tissue recovery 

Aid in circulation of nutrients to healing areas 

Papain contributes to the overall proteolytic activity of the Arto Velox blend, helping the body more efficiently manage protein accumulation associated with inflammation and injury.

Enzymes Plus Building Blocks: A Two-Phase Approach to Joint and Soft Tissue Support

While enzymes help regulate inflammation and support tissue cleanup, the body also needs raw materials to rebuild and maintain healthy joints and connective tissue. That’s why FORTE FLEX K9 pairs Arto Velox enzymes with clinically recognized joint-support nutrients:

Glucosamine: Supporting Cartilage Structure

Chondroitin: Supporting Joint Cushioning and Hydration

Collagen: Supporting Tendons, Ligaments, and Soft Tissue

Hyaluronic Acid (HA): Supporting Joint Lubrication

Why This Combination Matters for Canine Mobility?

Many joint supplements focus only on cartilage nutrients, while others focus only on inflammation. FORTE FLEX K9 is designed to address both sides of the equation:  

 -Arto Velox enzymes help manage inflammation and tissue cleanup   

 -Structural nutrients provide the building blocks for repair and joint integrity   

This comprehensive approach supports dogs with: 

Arthritis and degenerative joint disease 

Hip and elbow dysplasia 

CCL or ligament strain 

Post-surgical recovery 

High athletic demands 

Age-related stiffness and reduced mobility       

By supporting both biochemical balance and physical rebuilding, FORTE FLEX K9 promotes more complete and sustainable mobility support.

Conclusion: Supporting Recovery and Comfort from the Inside Out

Healthy movement depends on more than just cartilage — it depends on how effectively the body can manage inflammation, repair tissue, and maintain joint lubrication. The Arto Velox enzyme blend in FORTE FLEX K9 supports the body’s natural inflammatory response and recovery processes, while glucosamine, chondroitin, collagen, and hyaluronic acid provide the essential building blocks needed to maintain strong, resilient joints and connective tissue. Together, these ingredients create a powerful, science-driven approach to canine mobility, helping dogs stay active, comfortable, and confident throughout every stage of life. For pet parents seeking advanced, whole-body joint and recovery support, FORTE FLEX K9 offers a truly comprehensive solution.